Extending the MR‐Egger method for multivariable Mendelian randomization to correct for both measured and unmeasured pleiotropy

Methods have been developed for Mendelian randomization that can obtain consistent causal estimates while relaxing the instrumental variable assumptions. These include multivariable Mendelian randomization, in which a genetic variant may be associated with multiple risk factors so long as any associ...

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Detalles Bibliográficos
Autores principales: Rees, Jessica M. B., Wood, Angela M., Burgess, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725762/
https://www.ncbi.nlm.nih.gov/pubmed/28960498
http://dx.doi.org/10.1002/sim.7492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725762/
https://www.ncbi.nlm.nih.gov/pubmed/28960498
http://dx.doi.org/10.1002/sim.7492

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