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Asiatic acid attenuates methamphetamine-induced neuroinflammation and neurotoxicity through blocking of NF-kB/STAT3/ERK and mitochondria-mediated apoptosis pathway

BACKGROUND: Methamphetamine (METH) is a commonly abused drug that may result in neurotoxic effects. Recent studies have suggested that involvement of neuroinflammatory processes in brain dysfunction is induced by misuse of this drug. However, the mechanism underlying METH-induced inflammation and ne...

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Detalles Bibliográficos
Autores principales: Park, Ji-Hyun, Seo, Young Ho, Jang, Jung-Hee, Jeong, Chul-Ho, Lee, Sooyeun, Park, Byoungduck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725763/
https://www.ncbi.nlm.nih.gov/pubmed/29228978
http://dx.doi.org/10.1186/s12974-017-1009-0