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Dissecting cellular senescence and SASP in Drosophila

Cellular senescence can act as both tumor suppressor and tumor promoter depending on the cellular contexts. On one hand, premature senescence has been considered as an innate host defense mechanism against carcinogenesis in mammals. In response to various stresses including oxidative stress, DNA dam...

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Detalles Bibliográficos
Autores principales: Ito, Takao, Igaki, Tatsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725765/
https://www.ncbi.nlm.nih.gov/pubmed/29259698
http://dx.doi.org/10.1186/s41232-016-0031-4