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Genetic polymorphism in ATG16L1 gene is associated with adalimumab use in inflammatory bowel disease

BACKGROUND: The role of single nucleotide polymorphisms (SNPs) associated with inflammatory bowel disease (IBD) is gaining interest. With the advent of novel therapies, personalized treatment in IBD is a future goal. We wondered whether IBD-associated SNPs are able to predict response to anti-TNFα t...

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Detalles Bibliográficos
Autores principales: Nuij, V. J. A. A., Peppelenbosch, M. P., van der Woude, C. J., Fuhler, G. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725822/
https://www.ncbi.nlm.nih.gov/pubmed/29228965
http://dx.doi.org/10.1186/s12967-017-1355-9