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Complement-targeted therapy: development of C5- and C5a-targeted inhibition

The complement system is a major effector of humoral immunity and natural immunity. The complement system has three independent pathways of complement activation: a classical pathway, an alternative pathway, and a lectin pathway. These pathways converge to a common pathway that activates C3. This pa...

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Detalles Bibliográficos
Autores principales: Horiuchi, Takahiko, Tsukamoto, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725830/
https://www.ncbi.nlm.nih.gov/pubmed/29259684
http://dx.doi.org/10.1186/s41232-016-0013-6