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Complement-targeted therapy: development of C5- and C5a-targeted inhibition
The complement system is a major effector of humoral immunity and natural immunity. The complement system has three independent pathways of complement activation: a classical pathway, an alternative pathway, and a lectin pathway. These pathways converge to a common pathway that activates C3. This pa...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725830/ https://www.ncbi.nlm.nih.gov/pubmed/29259684 http://dx.doi.org/10.1186/s41232-016-0013-6 |