A simple and accurate rule-based modeling framework for simulation of autocrine/paracrine stimulation of glioblastoma cell motility and proliferation by L1CAM in 2-D culture

BACKGROUND: Glioblastoma multiforme (GBM) is a devastating brain cancer for which there is no known cure. Its malignancy is due to rapid cell division along with high motility and invasiveness of cells into the brain tissue. Simple 2-dimensional laboratory assays (e.g., a scratch assay) commonly are...

Descripción completa

Detalles Bibliográficos
Autores principales: Caccavale, Justin, Fiumara, David, Stapf, Michael, Sweitzer, Liedeke, Anderson, Hannah J., Gorky, Jonathan, Dhurjati, Prasad, Galileo, Deni S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725844/
https://www.ncbi.nlm.nih.gov/pubmed/29228953
http://dx.doi.org/10.1186/s12918-017-0516-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725844/
https://www.ncbi.nlm.nih.gov/pubmed/29228953
http://dx.doi.org/10.1186/s12918-017-0516-z

Ejemplares similares