Prostaglandin E(2)-EP2 signaling as a node of chronic inflammation in the colon tumor microenvironment

BACKGROUND: Colorectal cancer is the third most common cancer. Involvement of prostaglandin (PG) system in the pathogenesis of colorectal cancer has been suggested from clinical studies demonstrating therapeutic effect of NSAIDs including aspirin or selective COX-2 inhibitors. However, mechanisms on...

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Detalles Bibliográficos
Autores principales: Aoki, Tomohiro, Narumiya, Shuh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725845/
https://www.ncbi.nlm.nih.gov/pubmed/29259703
http://dx.doi.org/10.1186/s41232-017-0036-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725845/
https://www.ncbi.nlm.nih.gov/pubmed/29259703
http://dx.doi.org/10.1186/s41232-017-0036-7

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