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Prostaglandin E(2)-EP2 signaling as a node of chronic inflammation in the colon tumor microenvironment
BACKGROUND: Colorectal cancer is the third most common cancer. Involvement of prostaglandin (PG) system in the pathogenesis of colorectal cancer has been suggested from clinical studies demonstrating therapeutic effect of NSAIDs including aspirin or selective COX-2 inhibitors. However, mechanisms on...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725845/ https://www.ncbi.nlm.nih.gov/pubmed/29259703 http://dx.doi.org/10.1186/s41232-017-0036-7 |