Effects of CTLA4-Ig on human monocytes

BACKGROUND: Abatacept, a CTLA4-Ig fusion protein attenuates T cell activation by inhibiting the CD80/86-CD28 costimulatory pathway that is required for the proper T cell activation and thus displays beneficial effects in the treatment of rheumatoid arthritis (RA). Although some studies have disclose...

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Detalles Bibliográficos
Autores principales: Tono, Toshihiro, Aihara, Satoko, Hoshiyama, Takayuki, Arinuma, Yoshiyuki, Nagai, Tatsuo, Hirohata, Shunsei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725919/
https://www.ncbi.nlm.nih.gov/pubmed/29259723
http://dx.doi.org/10.1186/s41232-017-0054-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725919/
https://www.ncbi.nlm.nih.gov/pubmed/29259723
http://dx.doi.org/10.1186/s41232-017-0054-5

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