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Visualization of the lymphocytic choriomeningitis mammarenavirus (LCMV) genome reveals the early endosome as a possible site for genome replication and viral particle  pre-assembly

We report a fluorescence in situ hybridization (FISH) assay that allows the visualization of lymphocytic choriomeningitis mammarenavirus (LCMV) genomic RNAs in individual cells. We show that viral S segment genomic and antigenomic RNA, along with viral nucleoprotein, colocalize in subcellular struct...

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Detalles Bibliográficos
Autores principales: King, Benjamin R., Kellner, Samuel, Eisenhauer, Philip L., Bruce, Emily A., Ziegler, Christopher M., Zenklusen, Daniel, Botten, Jason William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725993/
https://www.ncbi.nlm.nih.gov/pubmed/28949905
http://dx.doi.org/10.1099/jgv.0.000930