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Visualization of the lymphocytic choriomeningitis mammarenavirus (LCMV) genome reveals the early endosome as a possible site for genome replication and viral particle pre-assembly
We report a fluorescence in situ hybridization (FISH) assay that allows the visualization of lymphocytic choriomeningitis mammarenavirus (LCMV) genomic RNAs in individual cells. We show that viral S segment genomic and antigenomic RNA, along with viral nucleoprotein, colocalize in subcellular struct...
Autores principales: | King, Benjamin R., Kellner, Samuel, Eisenhauer, Philip L., Bruce, Emily A., Ziegler, Christopher M., Zenklusen, Daniel, Botten, Jason William |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Microbiology Society
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725993/ https://www.ncbi.nlm.nih.gov/pubmed/28949905 http://dx.doi.org/10.1099/jgv.0.000930 |
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