Manipulation of both virus- and cell-specific factors is required for robust transient replication of a hepatitis C virus genotype 3a sub-genomic replicon

Hepatitis C virus (HCV) genotype (GT) 3 is the second most prevalent of the seven HCV genotypes and exhibits the greatest resistance to the highly potent, direct-acting antivirals (DAAs) that are currently in use. Previously a stable cell line harbouring the S52 GT3 sub-genomic replicon (SGR) was es...

Descripción completa

Detalles Bibliográficos
Autores principales: Kelly, Lorna, Badhan, Anjna, Roberts, Grace C., Mbisa, Jean Lutamyo, Harris, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725995/
https://www.ncbi.nlm.nih.gov/pubmed/28984238
http://dx.doi.org/10.1099/jgv.0.000932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725995/
https://www.ncbi.nlm.nih.gov/pubmed/28984238
http://dx.doi.org/10.1099/jgv.0.000932

Ejemplares similares