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Manipulation of both virus- and cell-specific factors is required for robust transient replication of a hepatitis C virus genotype 3a sub-genomic replicon

Hepatitis C virus (HCV) genotype (GT) 3 is the second most prevalent of the seven HCV genotypes and exhibits the greatest resistance to the highly potent, direct-acting antivirals (DAAs) that are currently in use. Previously a stable cell line harbouring the S52 GT3 sub-genomic replicon (SGR) was es...

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Detalles Bibliográficos
Autores principales:	Kelly, Lorna, Badhan, Anjna, Roberts, Grace C., Mbisa, Jean Lutamyo, Harris, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Microbiology Society 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725995/ https://www.ncbi.nlm.nih.gov/pubmed/28984238 http://dx.doi.org/10.1099/jgv.0.000932

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