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Selection, characterization, and thermal stabilization of llama single domain antibodies towards Ebola virus glycoprotein

BACKGROUND: A key advantage of recombinant antibody technology is the ability to optimize and tailor reagents. Single domain antibodies (sdAbs), the recombinantly produced variable domains derived from camelid and shark heavy chain antibodies, provide advantages of stability and solubility and can b...

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Detalles Bibliográficos
Autores principales: Liu, Jinny L., Shriver-Lake, Lisa C., Anderson, George P., Zabetakis, Dan, Goldman, Ellen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726015/
https://www.ncbi.nlm.nih.gov/pubmed/29233140
http://dx.doi.org/10.1186/s12934-017-0837-z