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Selection, characterization, and thermal stabilization of llama single domain antibodies towards Ebola virus glycoprotein
BACKGROUND: A key advantage of recombinant antibody technology is the ability to optimize and tailor reagents. Single domain antibodies (sdAbs), the recombinantly produced variable domains derived from camelid and shark heavy chain antibodies, provide advantages of stability and solubility and can b...
Autores principales: | Liu, Jinny L., Shriver-Lake, Lisa C., Anderson, George P., Zabetakis, Dan, Goldman, Ellen R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726015/ https://www.ncbi.nlm.nih.gov/pubmed/29233140 http://dx.doi.org/10.1186/s12934-017-0837-z |
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