Suppression of interleukin-6 increases enterovirus A71 lethality in mice

BACKGROUND: Enterovirus A71 (EV-A71) infection can induce fatal encephalitis in young children. Clinical reports show that interleukin-6 (IL-6) levels in the serum and cerebrospinal fluid of infected patients with brainstem encephalitis are significantly elevated. We used a murine model to address t...

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Detalles Bibliográficos
Autores principales: Wang, Li-Chiu, Yao, Hui-Wen, Chang, Chuan-Fa, Wang, Shainn-Wei, Wang, Shih-Min, Chen, Shun-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726025/
https://www.ncbi.nlm.nih.gov/pubmed/29233145
http://dx.doi.org/10.1186/s12929-017-0401-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726025/
https://www.ncbi.nlm.nih.gov/pubmed/29233145
http://dx.doi.org/10.1186/s12929-017-0401-5

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