The CLOSED trial; CLOnidine compared with midazolam for SEDation of paediatric patients in the intensive care unit: study protocol for a multicentre randomised controlled trial

INTRODUCTION: Sedation is an essential part of paediatric critical care. Midazolam, often in combination with opioids, is the current gold standard drug. However, as it is a far-from-ideal agent, clonidine is increasingly being used in children. This drug is prescribed off-label for this indication,...

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Detalles Bibliográficos
Autores principales: Neubert, Antje, Baarslag, Manuel Alberto, van Dijk, Monique, van Rosmalen, Joost, Standing, Joseph F, Sheng, Yucheng, Rascher, Wolfgang, Roberts, Deborah, Winslade, Jackie, Rawcliffe, Louise, Hanning, Sara M, Metsvaht, Tuuli, Giannuzzi, Viviana, Larsson, Peter, Pokorná, Pavla, Simonetti, Alessandra, Tibboel, Dick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Paediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726127/
https://www.ncbi.nlm.nih.gov/pubmed/28637741
http://dx.doi.org/10.1136/bmjopen-2017-016031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726127/
https://www.ncbi.nlm.nih.gov/pubmed/28637741
http://dx.doi.org/10.1136/bmjopen-2017-016031

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