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Corticosteroids in sepsis: an updated systematic review and meta-analysis (protocol)

INTRODUCTION: Sepsis is associated with a dysregulated host response to infection and impaired endogenous corticosteroid metabolism. As such, therapeutic use of exogenous corticosteroids is a promising adjunctive intervention. Despite a large number of trials examining this research question, uncert...

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Detalles Bibliográficos
Autores principales: Rochwerg, Bram, Oczkowski, Simon, Siemieniuk, Reed Alexander, Menon, Kusum, Szczeklik, Wojciech, English, Shane, Agoritsas, Thomas, Belley-Cote, Emilie, D’Aragon, Frédérick, Alhazzani, Waleed, Duan, Erick, Gossack-Keenan, Kira, Sevransky, Jon, Vandvik, Per, Venkatesh, Bala, Guyatt, Gordon, Annane, Djillali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726130/
https://www.ncbi.nlm.nih.gov/pubmed/28667229
http://dx.doi.org/10.1136/bmjopen-2017-016847