The mineralocorticoid receptor knockout in medaka is further validated by glucocorticoid receptor compensation

To study the critical role of mineralocorticoid signalling, we generated a constitutive mineralocorticoid receptor (MR)-knockout (KO) medaka as the first adult-viable MR-KO animal. This KO medaka displayed abnormal behaviours affected by visual stimuli. In contrast, the loss of MR did not result in...

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Detalles Bibliográficos
Autores principales: Sakamoto, Tatsuya, Yoshiki, Madoka, Sakamoto, Hirotaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Data Descriptor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726310/
https://www.ncbi.nlm.nih.gov/pubmed/29231924
http://dx.doi.org/10.1038/sdata.2017.189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726310/
https://www.ncbi.nlm.nih.gov/pubmed/29231924
http://dx.doi.org/10.1038/sdata.2017.189

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