Redox-responsive and pH-sensitive nanoparticles enhanced stability and anticancer ability of erlotinib to treat lung cancer in vivo

PURPOSE: Erlotinib (ETB) is a well-established therapeutic for non-small-cell lung cancer (NSCLC). To overcome drug resistance and severe toxicities in the clinical application, redox-responsive and pH-sensitive nanoparticle drug delivery systems were designed for the encapsulation of ETB. METHODS:...

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Detalles Bibliográficos
Autores principales: Tan, Sheng, Wang, Guoxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726363/
https://www.ncbi.nlm.nih.gov/pubmed/29263650
http://dx.doi.org/10.2147/DDDT.S151422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726363/
https://www.ncbi.nlm.nih.gov/pubmed/29263650
http://dx.doi.org/10.2147/DDDT.S151422

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