Nascent peptide assists the ribosome in recognizing chemically distinct small molecules

Regulation of gene expression in response to the changing environment is critical for cell survival. For instance, binding of macrolide antibiotics to the ribosome promote the translation arrest at the leader ORFs ermCL and ermBL necessary for inducing antibiotic resistance genes ermC and ermB. Clad...

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Detalles Bibliográficos
Autores principales: Gupta, Pulkit, Liu, Bo, Klepacki, Dorota, Gupta, Vrinda, Schulten, Klaus, Mankin, Alexander S., Vázquez-Laslop, Nora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726394/
https://www.ncbi.nlm.nih.gov/pubmed/26727240
http://dx.doi.org/10.1038/nchembio.1998

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726394/
https://www.ncbi.nlm.nih.gov/pubmed/26727240
http://dx.doi.org/10.1038/nchembio.1998

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