Arid1b haploinsufficiency disrupts cortical interneuron development and mouse behavior

Haploinsufficiency of the AT-rich interactive domain 1B (ARID1B) gene causes autism spectrum disorder (ASD) and intellectual disability, however, the neurobiological basis for this is unknown. Here, we generated Arid1b knockout mice and examined heterozygotes to model human patients. Arid1b heterozy...

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Detalles Bibliográficos
Autores principales: Jung, Eui-Man, Moffat, Jeffrey Jay, Liu, Jinxu, Dravid, Shashank Manohar, Gurumurthy, Channabasavaiah, Kim, Woo-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726525/
https://www.ncbi.nlm.nih.gov/pubmed/29184203
http://dx.doi.org/10.1038/s41593-017-0013-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726525/
https://www.ncbi.nlm.nih.gov/pubmed/29184203
http://dx.doi.org/10.1038/s41593-017-0013-0

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