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Arid1b haploinsufficiency disrupts cortical interneuron development and mouse behavior
Haploinsufficiency of the AT-rich interactive domain 1B (ARID1B) gene causes autism spectrum disorder (ASD) and intellectual disability, however, the neurobiological basis for this is unknown. Here, we generated Arid1b knockout mice and examined heterozygotes to model human patients. Arid1b heterozy...
Autores principales: | Jung, Eui-Man, Moffat, Jeffrey Jay, Liu, Jinxu, Dravid, Shashank Manohar, Gurumurthy, Channabasavaiah, Kim, Woo-Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726525/ https://www.ncbi.nlm.nih.gov/pubmed/29184203 http://dx.doi.org/10.1038/s41593-017-0013-0 |
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