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Influence of Trp flipping on carbohydrate binding in lectins. An example on Aleuria aurantia lectin AAL

Protein–carbohydrate interactions are very often mediated by the stacking CH–π interactions involving the side chains of aromatic amino acids such as tryptophan (Trp), tyrosine (Tyr) or phenylalanine (Phe). Especially suitable for stacking is the Trp residue. Analysis of the PDB database shows Trp s...

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Detalles Bibliográficos
Autores principales: Houser, Josef, Kozmon, Stanislav, Mishra, Deepti, Mishra, Sushil K., Romano, Patrick R., Wimmerová, Michaela, Koča, Jaroslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726637/
https://www.ncbi.nlm.nih.gov/pubmed/29232414
http://dx.doi.org/10.1371/journal.pone.0189375