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Influence of Trp flipping on carbohydrate binding in lectins. An example on Aleuria aurantia lectin AAL
Protein–carbohydrate interactions are very often mediated by the stacking CH–π interactions involving the side chains of aromatic amino acids such as tryptophan (Trp), tyrosine (Tyr) or phenylalanine (Phe). Especially suitable for stacking is the Trp residue. Analysis of the PDB database shows Trp s...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726637/ https://www.ncbi.nlm.nih.gov/pubmed/29232414 http://dx.doi.org/10.1371/journal.pone.0189375 |