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Inhibition of GRP78 abrogates radioresistance in oropharyngeal carcinoma cells after EGFR inhibition by cetuximab

The EGFR-specific mAb cetuximab is one of the most effective treatments for oropharyngeal carcinoma, while patient responses to EGFR inhibitors given alone are modest. Combination treatment with radiation can improve the efficacy of treatment through increasing radiosensitivity, while resistance to...

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Detalles Bibliográficos
Autores principales: Sun, Chaonan, Han, Chuyang, Jiang, Yuanjun, Han, Ning, Zhang, Miao, Li, Guang, Qiao, Qiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726659/
https://www.ncbi.nlm.nih.gov/pubmed/29232380
http://dx.doi.org/10.1371/journal.pone.0188932