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A computational model for regulation of nanoscale glucan exposure in Candida albicans

Candida albicans is a virulent human opportunistic pathogen. It evades innate immune surveillance by masking an immunogenic cell wall polysaccharide, β-glucan, from recognition by the immunoreceptor Dectin-1. Glucan unmasking by the antifungal drug caspofungin leads to changes in the nanostructure o...

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Detalles Bibliográficos
Autores principales: Wester, Michael J., Lin, Jia, Neumann, Aaron K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726713/
https://www.ncbi.nlm.nih.gov/pubmed/29232689
http://dx.doi.org/10.1371/journal.pone.0188599