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A computational model for regulation of nanoscale glucan exposure in Candida albicans
Candida albicans is a virulent human opportunistic pathogen. It evades innate immune surveillance by masking an immunogenic cell wall polysaccharide, β-glucan, from recognition by the immunoreceptor Dectin-1. Glucan unmasking by the antifungal drug caspofungin leads to changes in the nanostructure o...
Autores principales: | Wester, Michael J., Lin, Jia, Neumann, Aaron K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726713/ https://www.ncbi.nlm.nih.gov/pubmed/29232689 http://dx.doi.org/10.1371/journal.pone.0188599 |
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