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Bioinformatic analysis reveals new determinants of antigenic 14-3-3 proteins and a novel antifungal strategy

The ubiquitously expressed 14-3-3 family of proteins is evolutionarily conserved from yeast to mammals. Their involvement in humoral and cellular immune responses is emerging through studies in drosophila and humans. In humans, a select group of 14-3-3 isoforms are antigenic; however the determinant...

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Detalles Bibliográficos
Autores principales: McGowan, Jenna E., Kratch, Jacqueline, Chattopadhyay, Saurabh, Joe, Bina, Conti, Heather R., Chakravarti, Ritu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726717/
https://www.ncbi.nlm.nih.gov/pubmed/29232712
http://dx.doi.org/10.1371/journal.pone.0189503