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Profound loss of neprilysin accompanied by decreased levels of neuropeptides and increased CRP in ulcerative colitis

Neprilysin (NEP, CD10) acts to limit excessive inflammation partly by hydrolyzing neuropeptides. Although deletion of NEP exacerbates intestinal inflammation in animal models, its role in ulcerative colitis (UC) is not well explored. Herein, we aimed to demonstrate changes in NEP and associated neur...

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Detalles Bibliográficos
Autores principales: Sargın, Zeynep Gök, Erin, Nuray, Tazegul, Gokhan, Elpek, Gülsüm Özlem, Yıldırım, Bülent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726735/
https://www.ncbi.nlm.nih.gov/pubmed/29232715
http://dx.doi.org/10.1371/journal.pone.0189526