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Profound loss of neprilysin accompanied by decreased levels of neuropeptides and increased CRP in ulcerative colitis
Neprilysin (NEP, CD10) acts to limit excessive inflammation partly by hydrolyzing neuropeptides. Although deletion of NEP exacerbates intestinal inflammation in animal models, its role in ulcerative colitis (UC) is not well explored. Herein, we aimed to demonstrate changes in NEP and associated neur...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726735/ https://www.ncbi.nlm.nih.gov/pubmed/29232715 http://dx.doi.org/10.1371/journal.pone.0189526 |