Yeast eIF4A enhances recruitment of mRNAs regardless of their structural complexity

eIF4A is a DEAD-box RNA-dependent ATPase thought to unwind RNA secondary structure in the 5'-untranslated regions (UTRs) of mRNAs to promote their recruitment to the eukaryotic translation pre-initiation complex (PIC). We show that eIF4A's ATPase activity is markedly stimulated in the pres...

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Detalles Bibliográficos
Autores principales: Yourik, Paul, Aitken, Colin Echeverría, Zhou, Fujun, Gupta, Neha, Hinnebusch, Alan G, Lorsch, Jon R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726853/
https://www.ncbi.nlm.nih.gov/pubmed/29192585
http://dx.doi.org/10.7554/eLife.31476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726853/
https://www.ncbi.nlm.nih.gov/pubmed/29192585
http://dx.doi.org/10.7554/eLife.31476

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