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Delivery Pathway Regulation of 3′,3″-Bis-Peptide-siRNA Conjugate via Nanocarrier Architecture Engineering

Small interfering RNA (siRNA) has been continuously explored for clinical applications. However, neither nanocarriers nor conjugates have been able to remove the obstacles. In this study, we employed a combined nanochemistry strategy to optimize its delivery dilemma, where different interactions and...

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Detalles Bibliográficos
Autores principales: Sun, Jing, Qiu, Chong, Diao, Yiping, Wei, Wei, Jin, Hongwei, Zheng, Yi, Wang, Jiancheng, Zhang, Lihe, Yang, Zhenjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726857/
https://www.ncbi.nlm.nih.gov/pubmed/29499958
http://dx.doi.org/10.1016/j.omtn.2017.11.002