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Top-down characterization of endogenous protein complexes with native proteomics

Protein complexes exhibit great diversity in protein membership, post-translational modifications and noncovalent cofactors, enabling them to function as the actuators of many important biological processes. The exposition of these molecular features with current methods lacks either throughput or m...

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Detalles Bibliográficos
Autores principales: Skinner, Owen S., Haverland, Nicole A., Fornelli, Luca, Melani, Rafael D., Do Vale, Luis H. F., Seckler, Henrique S., Doubleday, Peter F., Schachner, Luis F., Srzentić, Kristina, Kelleher, Neil L., Compton, Philip D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726920/
https://www.ncbi.nlm.nih.gov/pubmed/29131144
http://dx.doi.org/10.1038/nchembio.2515