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Top-down characterization of endogenous protein complexes with native proteomics
Protein complexes exhibit great diversity in protein membership, post-translational modifications and noncovalent cofactors, enabling them to function as the actuators of many important biological processes. The exposition of these molecular features with current methods lacks either throughput or m...
Autores principales: | Skinner, Owen S., Haverland, Nicole A., Fornelli, Luca, Melani, Rafael D., Do Vale, Luis H. F., Seckler, Henrique S., Doubleday, Peter F., Schachner, Luis F., Srzentić, Kristina, Kelleher, Neil L., Compton, Philip D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726920/ https://www.ncbi.nlm.nih.gov/pubmed/29131144 http://dx.doi.org/10.1038/nchembio.2515 |
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