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Race/ethnicity difference in the pharmacogenetics of bilirubin-related atazanavir discontinuation

BACKGROUND: Atazanavir causes plasma indirect bilirubin to increase. We evaluated associations between Gilbert’s polymorphism and bilirubin-related atazanavir discontinuation stratified by race/ethnicity. PATIENTS AND METHODS: Patients had initiated atazanavir/ritonavir-containing regimens at an HIV...

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Detalles Bibliográficos
Autores principales: Leger, Paul, Chirwa, Sanika, Nwogu, Jacinta N., Turner, Megan, Richardson, Danielle M., Baker, Paxton, Leonard, Michael, Erdem, Husamettin, Olson, Lana, Haas, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726942/
https://www.ncbi.nlm.nih.gov/pubmed/29117017
http://dx.doi.org/10.1097/FPC.0000000000000316