IRF8-dependent molecular complexes control the Th9 transcriptional program

Interferon regulatory factors (IRF) have critical functions in lymphoid development and in immune response regulation. Although many studies have described the function of IRF4 in CD4(+) T cells, few have focused on the IRF4 homologue, IRF8. Here, we show that IRF8 is required for Th9 differentiatio...

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Detalles Bibliográficos
Autores principales: Humblin, Etienne, Thibaudin, Marion, Chalmin, Fanny, Derangère, Valentin, Limagne, Emeric, Richard, Corentin, Flavell, Richard A., Chevrier, Sandy, Ladoire, Sylvain, Berger, Hélène, Boidot, Romain, Apetoh, Lionel, Végran, Frédérique, Ghiringhelli, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727025/
https://www.ncbi.nlm.nih.gov/pubmed/29233972
http://dx.doi.org/10.1038/s41467-017-01070-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727025/
https://www.ncbi.nlm.nih.gov/pubmed/29233972
http://dx.doi.org/10.1038/s41467-017-01070-w

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