Dynamic regulation of TREK1 gating by Polycystin 2 via a Filamin A-mediated cytoskeletal Mechanism

Mechanosensing is essential for several physiological functions including touch and pain sensations, osmoregulation, and controlling the myogenic tone of resistance arteries. Understanding how mechanosensitive ion channels (MSCs) are gated can provide important information regarding these processes....

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Detalles Bibliográficos
Autores principales: Li Fraine, Steven, Patel, Amanda, Duprat, Fabrice, Sharif-Naeini, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727099/
https://www.ncbi.nlm.nih.gov/pubmed/29234037
http://dx.doi.org/10.1038/s41598-017-16540-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727099/
https://www.ncbi.nlm.nih.gov/pubmed/29234037
http://dx.doi.org/10.1038/s41598-017-16540-w

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