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Highly enantioselective catalytic synthesis of chiral pyridines

General methods to prepare chiral pyridine derivatives are greatly sought after due to their significance in medicinal chemistry. Here, we report highly enantioselective catalytic transformations of poorly reactive β-substituted alkenyl pyridines to access a wide range of alkylated chiral pyridines....

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Detalles Bibliográficos
Autores principales: Jumde, Ravindra P., Lanza, Francesco, Pellegrini, Tilde, Harutyunyan, Syuzanna R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727103/
https://www.ncbi.nlm.nih.gov/pubmed/29233959
http://dx.doi.org/10.1038/s41467-017-01966-7