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Cross-Protective Efficacy of Influenza Virus M2e Containing Virus-Like Particles Is Superior to Hemagglutinin Vaccines and Variable Depending on the Genetic Backgrounds of Mice

Influenza virus M2 extracellular domain (M2e) has been a target for developing cross-protective vaccines. However, the efficacy and immune correlates of M2e vaccination are poorly understood in the different host genetic backgrounds in comparison with influenza vaccines. We previously reported the c...

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Detalles Bibliográficos
Autores principales: Kim, Yu-Jin, Lee, Young-Tae, Kim, Min-Chul, Lee, Yu-Na, Kim, Ki-Hye, Ko, Eun-Ju, Song, Jae-Min, Kang, Sang-Moo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727122/
https://www.ncbi.nlm.nih.gov/pubmed/29276514
http://dx.doi.org/10.3389/fimmu.2017.01730