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High efficiency and long-term intracellular activity of an enzymatic nanofactory based on metal-organic frameworks

Enhancing or restoring enzymatic function in cells is highly desirable in applications ranging from ex vivo cellular manipulations to enzyme replacement therapies in humans. However, because enzymes degrade in biological milieus, achieving long-term enzymatic activities can be challenging. Herein we...

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Detalles Bibliográficos
Autores principales: Lian, Xizhen, Erazo-Oliveras, Alfredo, Pellois, Jean-Philippe, Zhou, Hong-Cai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727123/
https://www.ncbi.nlm.nih.gov/pubmed/29234027
http://dx.doi.org/10.1038/s41467-017-02103-0