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Lipoteichoic acid deficiency permits normal growth but impairs virulence of Streptococcus pneumoniae

Teichoic acid (TA), a crucial cell wall constituent of the pathobiont Streptococcus pneumoniae, is bound to peptidoglycan (wall teichoic acid, WTA) or to membrane glycolipids (lipoteichoic acid, LTA). Both TA polymers share a common precursor synthesis pathway, but differ in the final transfer of th...

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Detalles Bibliográficos
Autores principales: Heß, Nathalie, Waldow, Franziska, Kohler, Thomas P., Rohde, Manfred, Kreikemeyer, Bernd, Gómez-Mejia, Alejandro, Hain, Torsten, Schwudke, Dominik, Vollmer, Waldemar, Hammerschmidt, Sven, Gisch, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727136/
https://www.ncbi.nlm.nih.gov/pubmed/29233962
http://dx.doi.org/10.1038/s41467-017-01720-z