Inhibition of NHEJ repair by type II-A CRISPR-Cas systems in bacteria

Type II CRISPR-Cas systems introduce double-strand breaks into DNA of invading genetic material and use DNA fragments to acquire novel spacers during adaptation. These breaks can be the substrate of several DNA repair pathways, paving the way for interactions. We report that non-homologous end-joini...

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Detalles Bibliográficos
Autores principales: Bernheim, Aude, Calvo-Villamañán, Alicia, Basier, Clovis, Cui, Lun, Rocha, Eduardo P. C., Touchon, Marie, Bikard, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727150/
https://www.ncbi.nlm.nih.gov/pubmed/29234047
http://dx.doi.org/10.1038/s41467-017-02350-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727150/
https://www.ncbi.nlm.nih.gov/pubmed/29234047
http://dx.doi.org/10.1038/s41467-017-02350-1

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