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Inhibition of NHEJ repair by type II-A CRISPR-Cas systems in bacteria
Type II CRISPR-Cas systems introduce double-strand breaks into DNA of invading genetic material and use DNA fragments to acquire novel spacers during adaptation. These breaks can be the substrate of several DNA repair pathways, paving the way for interactions. We report that non-homologous end-joini...
Autores principales: | Bernheim, Aude, Calvo-Villamañán, Alicia, Basier, Clovis, Cui, Lun, Rocha, Eduardo P. C., Touchon, Marie, Bikard, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727150/ https://www.ncbi.nlm.nih.gov/pubmed/29234047 http://dx.doi.org/10.1038/s41467-017-02350-1 |
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