Cargando…

Inhibition of NHEJ repair by type II-A CRISPR-Cas systems in bacteria

Type II CRISPR-Cas systems introduce double-strand breaks into DNA of invading genetic material and use DNA fragments to acquire novel spacers during adaptation. These breaks can be the substrate of several DNA repair pathways, paving the way for interactions. We report that non-homologous end-joini...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bernheim, Aude, Calvo-Villamañán, Alicia, Basier, Clovis, Cui, Lun, Rocha, Eduardo P. C., Touchon, Marie, Bikard, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727150/ https://www.ncbi.nlm.nih.gov/pubmed/29234047 http://dx.doi.org/10.1038/s41467-017-02350-1

Ejemplares similares

A matter of background: DNA repair pathways as a possible cause for the sparse distribution of CRISPR-Cas systems in bacteria
por: Bernheim, Aude, et al.
Publicado: (2019)

Atypical organizations and epistatic interactions of CRISPRs and cas clusters in genomes and their mobile genetic elements
por: Bernheim, Aude, et al.
Publicado: (2020)

On-target activity predictions enable improved CRISPR–dCas9 screens in bacteria
por: Calvo-Villamañán, Alicia, et al.
Publicado: (2020)

Genetic and life-history traits associated with the distribution of prophages in bacteria
por: Touchon, Marie, et al.
Publicado: (2016)

CRISPR-Cas9 Can Inhibit HIV-1 Replication but NHEJ Repair Facilitates Virus Escape
por: Wang, Gang, et al.
Publicado: (2016)

Genetic exchanges are more frequent in bacteria encoding capsules
por: Rendueles, Olaya, et al.
Publicado: (2018)

Analysis of NHEJ-Based DNA Repair after CRISPR-Mediated DNA Cleavage
por: Song, Beomjong, et al.
Publicado: (2021)

Control of gene expression by CRISPR-Cas systems
por: Bikard, David, et al.
Publicado: (2013)

Repair of chromosomal breaks by NHEJ
por: Reid, Dylan A., et al.
Publicado: (2015)

In Vitro and In Vivo Genetic Disease Modeling via NHEJ-Precise Deletions Using CRISPR-Cas9
por: López-Manzaneda, Sergio, et al.
Publicado: (2020)

Dynamics and competition of CRISPR–Cas9 ribonucleoproteins and AAV donor-mediated NHEJ, MMEJ and HDR editing
por: Fu, Ya-Wen, et al.
Publicado: (2021)

Stress-inducible NHEJ in bacteria: function in DNA repair and acquisition of heterologous DNA
por: Dupuy, Pierre, et al.
Publicado: (2019)

Consequences of Cas9 cleavage in the chromosome of Escherichia coli
por: Cui, Lun, et al.
Publicado: (2016)

Genome-wide CRISPR-dCas9 screens in E. coli identify essential genes and phage host factors
por: Rousset, François, et al.
Publicado: (2018)

The Small, Slow and Specialized CRISPR and Anti-CRISPR of Escherichia and Salmonella
por: Touchon, Marie, et al.
Publicado: (2010)

MacSyFinder: A Program to Mine Genomes for Molecular Systems with an Application to CRISPR-Cas Systems
por: Abby, Sophie S., et al.
Publicado: (2014)

CRISPRCasFinder, an update of CRISRFinder, includes a portable version, enhanced performance and integrates search for Cas proteins
por: Couvin, David, et al.
Publicado: (2018)

CRISPR-Cas9 fusion to dominant-negative 53BP1 enhances HDR and inhibits NHEJ specifically at Cas9 target sites
por: Jayavaradhan, Rajeswari, et al.
Publicado: (2019)

Precise exogenous insertion and sequence replacements in poplar by simultaneous HDR overexpression and NHEJ suppression using CRISPR-Cas9
por: Movahedi, Ali, et al.
Publicado: (2022)

Cas9 specifies functional viral targets during CRISPR-Cas adaptation
por: Heler, Robert, et al.
Publicado: (2015)

Suppressing the NHEJ pathway by DNA-PKcs inhibitor NU7026 prevents degradation of HBV cccDNA cleaved by CRISPR/Cas9
por: Kostyushev, Dmitry, et al.
Publicado: (2019)

Conditional tolerance of temperate phages via transcription-dependent CRISPR-Cas targeting
por: Goldberg, Gregory W., et al.
Publicado: (2014)

The cell cycle and cell size influence the rates of global cellular translation and transcription in fission yeast
por: Basier, Clovis, et al.
Publicado: (2023)

Molecular basis for DNA strand displacement by NHEJ repair polymerases
por: Bartlett, Edward J., et al.
Publicado: (2016)

Cryo-EM of NHEJ supercomplexes provides insights into DNA repair
por: Chaplin, Amanda K., et al.
Publicado: (2021)

The Application of NHEJ-CRISPR/Cas9 and Cre-Lox System in the Generation of Bivalent Duck Enteritis Virus Vaccine against Avian Influenza Virus
por: Chang, Pengxiang, et al.
Publicado: (2018)

Application of different types of CRISPR/Cas-based systems in bacteria
por: Liu, Zhenquan, et al.
Publicado: (2020)

Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system
por: Bikard, David, et al.
Publicado: (2013)

Programmable CRISPR‐Cas transcriptional activation in bacteria
por: Ho, Hsing‐I, et al.
Publicado: (2020)

Editorial: CRISPR-Cas Systems in Bacteria and Archaea
por: Kamruzzaman, Muhammad, et al.
Publicado: (2022)

Genome Editing in Bacteria: CRISPR-Cas and Beyond
por: Arroyo-Olarte, Ruben D., et al.
Publicado: (2021)

CRISPR-Cas9/Cas12a biotechnology and application in bacteria
por: Yao, Ruilian, et al.
Publicado: (2018)

Development of sequence-specific antimicrobials based on programmable CRISPR-Cas nucleases
por: Bikard, David, et al.
Publicado: (2014)

Tuning dCas9's ability to block transcription enables robust, noiseless knockdown of bacterial genes
por: Vigouroux, Antoine, et al.
Publicado: (2018)

CRISPR-Cas12a-Assisted Recombineering in Bacteria
por: Yan, Mei-Yi, et al.
Publicado: (2017)

Alternative-NHEJ Is a Mechanistically Distinct Pathway of Mammalian Chromosome Break Repair
por: Bennardo, Nicole, et al.
Publicado: (2008)

Regulation of DNA Repair pathway choice in S/G2 by the NHEJ inhibitor CYREN
por: Arnoult, Nausica, et al.
Publicado: (2017)

Impaired NHEJ repair in amyotrophic lateral sclerosis is associated with TDP-43 mutations
por: Konopka, Anna, et al.
Publicado: (2020)

Metastasis Suppressor NME1 Modulates Choice of Double-Strand Break Repair Pathways in Melanoma Cells by Enhancing Alternative NHEJ while Inhibiting NHEJ and HR
por: Puts, Gemma, et al.
Publicado: (2020)

A CRISPRi screen in E. coli reveals sequence-specific toxicity of dCas9
por: Cui, Lun, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_54ld97krol1e1v67uf7ggevajg