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Identification of two novel genes SLC15A2 and SLCO1B3 associated with maintenance dose variability of warfarin in a Chinese population

Warfarin is a commonly prescribed and effective oral anticoagulant. Genetic polymorphisms associated with warfarin metabolism and sensitivity have been implicated in the wide inter-individual dose variation that is observed. Several algorithms integrating patients’ clinical characteristics and genet...

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Detalles Bibliográficos
Autores principales: Cai, Liang-Liang, Huang, Wen-Qing, Su, Zhi-Ying, Ye, Hui-Ming, Wang, Lian-Sheng, Wu, Yuan, Zhang, Zhong-Ying, Zhang, Wei, Tzeng, Chi-Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727167/
https://www.ncbi.nlm.nih.gov/pubmed/29234073
http://dx.doi.org/10.1038/s41598-017-17731-1