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Cannabinoid type 2 receptors in dopamine neurons inhibits psychomotor behaviors, alters anxiety, depression and alcohol preference

Cannabinoid CB2 receptors (CB2Rs) are expressed in mouse brain dopamine (DA) neurons and are involved in several DA-related disorders. However, the cell type-specific mechanisms are unclear since the CB2R gene knockout mice are constitutive gene knockout. Therefore, we generated Cnr2-floxed mice tha...

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Detalles Bibliográficos
Autores principales: Liu, Qing-Rong, Canseco-Alba, Ana, Zhang, Hai-Ying, Tagliaferro, Patricia, Chung, Monika, Dennis, Eugene, Sanabria, Branden, Schanz, Norman, Escosteguy-Neto, Joao Carlos, Ishiguro, Hiroki, Lin, Zhicheng, Sgro, Susan, Leonard, Claire M., Santos-Junior, Jair Guilherme, Gardner, Eliot L., Egan, Josephine M., Lee, Jeung Woon, Xi, Zheng-Xiong, Onaivi, Emmanuel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727179/
https://www.ncbi.nlm.nih.gov/pubmed/29234141
http://dx.doi.org/10.1038/s41598-017-17796-y