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Protein quantitative trait locus study in obesity during weight-loss identifies a leptin regulator
Thousands of genetic variants have been associated with complex traits through genome-wide association studies. However, the functional variants or mechanistic consequences remain elusive. Intermediate traits such as gene expression or protein levels are good proxies of the metabolic state of an org...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727191/ https://www.ncbi.nlm.nih.gov/pubmed/29234017 http://dx.doi.org/10.1038/s41467-017-02182-z |