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Complement C3a signaling facilitates skeletal muscle regeneration by regulating monocyte function and trafficking
Regeneration of skeletal muscle following injury is accompanied by transient inflammation. Here we show that complement is activated in skeletal muscle injury and plays a key role during regeneration. Genetic ablation of complement C3 or its inactivation with Cobra Venom Factor (CVF) result in impai...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727192/ https://www.ncbi.nlm.nih.gov/pubmed/29233958 http://dx.doi.org/10.1038/s41467-017-01526-z |