Complement C3a signaling facilitates skeletal muscle regeneration by regulating monocyte function and trafficking

Regeneration of skeletal muscle following injury is accompanied by transient inflammation. Here we show that complement is activated in skeletal muscle injury and plays a key role during regeneration. Genetic ablation of complement C3 or its inactivation with Cobra Venom Factor (CVF) result in impai...

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Detalles Bibliográficos
Autores principales: Zhang, Congcong, Wang, Chunxiao, Li, Yulin, Miwa, Takashi, Liu, Chang, Cui, Wei, Song, Wen-Chao, Du, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727192/
https://www.ncbi.nlm.nih.gov/pubmed/29233958
http://dx.doi.org/10.1038/s41467-017-01526-z

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