Loss of the molecular clock in myeloid cells exacerbates T cell-mediated CNS autoimmune disease

The transcription factor BMAL1 is a core component of the molecular clock, regulating biological pathways that drive 24 h (circadian) rhythms in behaviour and physiology. The molecular clock has a profound influence on innate immune function, and circadian disruption is linked with increased inciden...

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Detalles Bibliográficos
Autores principales: Sutton, Caroline E., Finlay, Conor M., Raverdeau, Mathilde, Early, James O., DeCourcey, Joseph, Zaslona, Zbigniew, O’Neill, Luke A. J., Mills, Kingston H. G., Curtis, Annie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727202/
https://www.ncbi.nlm.nih.gov/pubmed/29234010
http://dx.doi.org/10.1038/s41467-017-02111-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727202/
https://www.ncbi.nlm.nih.gov/pubmed/29234010
http://dx.doi.org/10.1038/s41467-017-02111-0

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