The Human DNA glycosylases NEIL1 and NEIL3 Excise Psoralen-Induced DNA-DNA Cross-Links in a Four-Stranded DNA Structure

Interstrand cross-links (ICLs) are highly cytotoxic DNA lesions that block DNA replication and transcription by preventing strand separation. Previously, we demonstrated that the bacterial and human DNA glycosylases Nei and NEIL1 excise unhooked psoralen-derived ICLs in three-stranded DNA via hydrol...

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Detalles Bibliográficos
Autores principales: Martin, Peter R., Couvé, Sophie, Zutterling, Caroline, Albelazi, Mustafa S., Groisman, Regina, Matkarimov, Bakhyt T., Parsons, Jason L., Elder, Rhoderick H., Saparbaev, Murat K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727206/
https://www.ncbi.nlm.nih.gov/pubmed/29234069
http://dx.doi.org/10.1038/s41598-017-17693-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727206/
https://www.ncbi.nlm.nih.gov/pubmed/29234069
http://dx.doi.org/10.1038/s41598-017-17693-4

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